Cognitive Behavior Therapy Augmentation of Pharmacotherapy in Pediatric Obsessive-Compulsive Disorder

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Pharmacotherapy for obsessive–compulsive disorder

Considered untreatable before the 1960s, obsessive–compulsive disorder (OCD) remains a common and enduring illness that can affect any age group (Skoog 1999). Pharmacotherapy for the disorder began in the 1960s, which saw the introduction of the tricyclic agent clomipramine. Treatment has since evolved, with selective serotonin reuptake inhibitors (SSRIs) in the 1980s and augmentation with anti...

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Pharmacotherapy for obsessive-compulsive disorder.

Pharmacotherapeutic options for obsessive-compulsive disorder (OCD) have expanded over the past half-century since medications were first found to be effective for the treatment of OCD. Currently, the serotonin reuptake inhibitors (SRIs) represent the first-line pharmacotherapy for OCD. High dosages and long trials of the SRIs are needed for adequate treatment of OCD. The use of SRIs for the tr...

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Cognitive-Behavioral Therapy of Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is characterized by the presence of obsessions and/or compulsions that consume time and significantly interfere with the individual's daily routines, work, family or social life, causing marked distress (American Psychiatric Association, 2002). Until the 1980s, OCD was considered a rare disorder. The ECA (Epidemiological Catchment Area) study estimated its pr...

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Cognitive behavioral therapy of obsessive-compulsive disorder

OBJECTIVE To describe the cognitive-behavioral therapy in the treatment of the symptoms of obsessive-compulsive disorder. METHOD Through the revision of text books and articles the origins and fundamentals of cognitive-behavioral therapy in the treatment of the symptoms of obsessive-compulsive disorder are presented. Through the review of randomized clinical trials and meta-analysis in Medlin...

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Sleep problems and cognitive behavior therapy in pediatric obsessive-compulsive disorder have bidirectional effects.

OBJECTIVES To investigate the presence of sleep problems and their reaction to CBT in pediatric obsessive compulsive disorder (OCD). Moreover, we investigated whether sleep problems predict the outcome of CBT on OCD-symptoms. METHODS 269 children and adolescents, age 7-17 years, with DSM-IV primary OCD that took part in the first step of a stepwise treatment trial, were assessed with regard t...

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ژورنال

عنوان ژورنال: JAMA

سال: 2011

ISSN: 0098-7484

DOI: 10.1001/jama.2011.1344